Cell Biology

Volume 7, Issue 2, December 2019

  • Menadione Induces DNA Damage and Superoxide Radical Level In HEK293 Cells

    Alireza Ghodsi Senejani, Joseph Matthew Magrino, Amanda Marston, Michelle Gregoire, Khoa Dang Dinh

    Issue: Volume 7, Issue 2, December 2019
    Pages: 14-22
    Received: 15 November 2019
    Accepted: 2 December 2019
    Published: 11 December 2019
    Abstract: Reactive oxygen species (ROS) can damage cellular components, including mitochondrial and genomic DNA. Oxidized DNA can transgress into lethal double stranded breaks if not adequately repaired. Clinical reports of the major neurodegenerative diseases have denoted the presence of oxidized genomic DNA with no clear understanding of their role in dise... Show More