Cell Biology

Volume 6, Issue 2, December 2018

  • Structure and Functions: ERM Protein Family

    Divine Mensah Sedzro, Sm Faysal Bellah, Hameed Akbar, Sardar Mohammad Saker Billah

    Issue: Volume 6, Issue 2, December 2018
    Pages: 20-32
    Received: 15 September 2018
    Accepted: 6 October 2018
    Published: 29 October 2018
    DOI: 10.11648/j.cb.20180602.11
    Abstract: Preservation of the structural integrity of the cell depends on the plasma membrane in eukaryotic cells. Interaction between plasma membrane, cytoskeleton and proper anchorage influence regular cellular processes. The needed regulated connection between the membrane and the underlying actin cytoskeleton is therefore made available by the ERM (Ezrin... Show More
  • Possible Hypothesis on Alzheimer’s Disease Pathogenesis and Its Link to Trisomy 21

    Endriyas Kelta Wabalo, Chala Kenenisa Edae

    Issue: Volume 6, Issue 2, December 2018
    Pages: 33-46
    Received: 9 November 2018
    Accepted: 19 December 2018
    Published: 4 January 2019
    DOI: 10.11648/j.cb.20180602.12
    Abstract: The presence of “plaques” and “tangles” in the brain is considered as the hallmark of Alzheimer’s disease. The major constituent of the plaques is a protein (“A-beta”) which is split off from a much larger parent protein called Amyloid Precursor Protein (APP), and that of tangles is the protein tau, which normally functions to stabilize microtubule... Show More