Cell Biology

Volume 2, Issue 6, November 2014

  • MiR-142-3p Regulates Cardiovascular System during Zebrafish Development

    Ziyad Tariq Muhseen, Nibras Najm Abbood

    Issue: Volume 2, Issue 6, November 2014
    Pages: 49-59
    Received: 2 November 2014
    Accepted: 30 November 2014
    Published: 18 December 2014
    Abstract: MicroRNA-142-3p (miR-142-3p) is considered to play key role in many cellular processes, such as proliferation, differentiation and apoptosis by inhibiting target gene expression. The transcriptional regulation of cardiovascular development requires precise spatiotemporal control of gene expression. We are beginning to understand the functions of mi... Show More
  • Extracellular Vesicles (EVs); Basic Science, Clinical Relevance and Applications

    Wael Nassar, Mervat El-Ansary, Mostafa Abdel Aziz

    Issue: Volume 2, Issue 6, November 2014
    Pages: 60-71
    Received: 29 November 2014
    Accepted: 16 December 2014
    Published: 22 December 2014
    Abstract: All types of cells of eukaryotic organisms produce and release small Nano-vesicles into their extracellular environment. Early studies have described these vesicles as “garbage bags” only to remove obsolete cellular molecules. Valadi and coworkers, in 2007, was the first who discovered the capability of circulating EVs to horizontally transfer func... Show More
  • Histological and Immunohistochemical Study on Human Placental Tissue in Normal Pregnancy and Preeclampsia

    Noha Abdellatif Ibrahim, Doaa Mabrouk Khaled

    Issue: Volume 2, Issue 6, November 2014
    Pages: 72-80
    Received: 7 December 2014
    Accepted: 17 December 2014
    Published: 31 December 2014
    Abstract: Background: Preeclampsia is a serious disorder affecting the mother. It may be responsible for more than 50,000 maternal deaths worldwide each year. It is a major killer of both mother and fetus. Aim: To demonstrate the morphological changes of human placental tissue in pre-eclamptic pregnancies compared with the normal by using histological and im... Show More