Cell Biology

Volume 2, Issue 4, July 2014

  • Telomere Length Differences upon Keratinization and its Variations in Normal Human Epidermal Keratinocytes

    Katsuhiro Hitomi

    Issue: Volume 2, Issue 4, July 2014
    Pages: 28-35
    Received: 20 August 2014
    Accepted: 6 September 2014
    Published: 20 September 2014
    Abstract: Telomeres are the physical ends of chromosomes, and are cleaved with each cell division. Telomere loss results from not only incomplete DNA replication (“end replication problem”), followed by the processing of chromosome, but also exposure to various DNA damaging agents. Human epidermis is constantly replaced through replication at the basal layer... Show More
  • Acute Oral Coumestrol Treatment Induces Sperm and Sex Steroid Alterations in Mice

    Hector Serrano, Guillermo Mora-Ramiro, Sheila Peña-Corona, Pablo León-Ortíz, Arturo Salame-Mendez, Enrique Mendieta-Márques, José Luis Gómez-Olivares, María Dolores García-Suárez

    Issue: Volume 2, Issue 4, July 2014
    Pages: 36-40
    Received: 8 September 2014
    Accepted: 20 September 2014
    Published: 30 September 2014
    Abstract: Plant phytoestrogens interfere with normal estrogen-regulated functions like steroid synthesis and gonad physiology and morphology. Much evidence has been obtained by using high dose treatments or in vitro exposure to phytoestrogens but little is known about low, dietary level concentrations of these compounds, particularly coumestrol. In order to ... Show More