The most important step of the cell life cycle is undoubtedly the cell death mechanisms that enable aging or unneeded cells to be eliminated from their environment without damaging the surrounding cells. This death mechanism that plays an important role in regulating the internal balance of multicellular organisms, is a normal process observed in the healthy development of multicellular organisms. Cell death mechanisms whose activity has been lost or decreased in uncontrolled proliferating cells can reveal a situation that can cost the living organism such as cancer. Especially in the treatment of cancer, it is important to re-operate these pathways and to run processes without damaging the solid structures in the organism. Advances in cancer treatments have paved the way for new discoveries. Direct targeting of cancer metabolism and treatment effect mechanisms also affects human quality of life positively. To investigate the mechanisms that contribute to the cancer process, the creation of experimental methods and treatments, and share the information obtained indicates the importance of steps taken against the disease. In our special issue titled Cell Death and Mechanisms in Cancer, which will be published under the journal Cell Biology, we hope to present new approaches to cancer treatment as well as new ideas to shed light on these approaches.

Aims and Scope:

1. Cancer biology and metabolism
2. Experimental medicine
3. Experimental cancer models
4. Immunity
5. Signal transduction
6. DNA damage and repair